A smart drug: a pH-responsive photothermal ablation agent for Golgi apparatus activated cancer therapy. Issue 48 (30th May 2017)
- Record Type:
- Journal Article
- Title:
- A smart drug: a pH-responsive photothermal ablation agent for Golgi apparatus activated cancer therapy. Issue 48 (30th May 2017)
- Main Title:
- A smart drug: a pH-responsive photothermal ablation agent for Golgi apparatus activated cancer therapy
- Authors:
- Xue, Fengfeng
Wen, Ying
Wei, Peng
Gao, Yilin
Zhou, Zhiguo
Xiao, Shuzhang
Yi, Tao - Abstract:
- Abstract : A pH-responsive photothermal ablation agent for Golgi apparatus activated cancer therapy with NIR excitation was developed. Abstract : We report a pH-responsive photothermal ablation agent (pH-PTT ) based on cyanine dyes for photothermal therapy (PTT). The nanoparticles formed by BSA andpH-PTT preferentially accumulated in the Golgi apparatus of cancer cells compared to normal cells, and thus can be specifically activated by the acidic Golgi apparatus in cancer cells for effective PTT both ex vivo and in vivo .
- Is Part Of:
- Chemical communications. Volume 53:Issue 48(2017)
- Journal:
- Chemical communications
- Issue:
- Volume 53:Issue 48(2017)
- Issue Display:
- Volume 53, Issue 48 (2017)
- Year:
- 2017
- Volume:
- 53
- Issue:
- 48
- Issue Sort Value:
- 2017-0053-0048-0000
- Page Start:
- 6424
- Page End:
- 6427
- Publication Date:
- 2017-05-30
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c7cc03168h ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 988.xml