Correlation of carbon dots' light-activated antimicrobial activities and fluorescence quantum yield. Issue 48 (12th June 2017)

• Record Type: Journal Article
• Authors: Al Awak, Mohamad M.; Wang, Ping; Wang, Shengyuan; Tang, Yongan; Sun, Ya-Ping; Yang, Liju
• Is Part Of: RSC advances. Volume 7:Issue 48(2017)
• Page Start: 30177
• Page End: 30184
• Publication Date: 2017-06-12
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c7ra05397e
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : The antibacterial performance of carbon dots is correlated with their photoexcited state properties for mechanistic elucidation. Abstract : This study investigated the photo-activated antibacterial function of a series of specifically prepared carbon dots with 2, 2′-(ethylenedioxy)bis(ethylamine) as the surface functionalization molecule (EDA-CDots), whose fluorescence quantum yields ( Φ F ) ranged from 7.5% to 27%. The results revealed that the effectiveness of CDots' photo-activated bactericidal function was correlated with their observed Φ F values. The antimicrobial activities of these EDA-CDots against both Gram negative and Gram positive model bacterial species ( E. coli and Bacillus subtilis, respectively) were also evaluated under conditions of varying other experimental parameters including dot concentrations and treatment times. Optimization of the bactericidal effect of the EDA-CDots by a combination of the selected Φ F, concentration and treatment time was explored, and mechanistic implications of the results are discussed.