Parallel and antiparallel cyclic d/l peptide nanotubes. Issue 49 (5th June 2017)

• Record Type: Journal Article
• Authors: Silk, Mitchell R.; Newman, Janet; Ratcliffe, Julian C.; White, Jacinta F.; Caradoc-Davies, Tom; Price, Jason R.; Perrier, Sébastien; Thompson, Philip E.; Chalmers, David K.
• Is Part Of: Chemical communications. Volume 53:Issue 49(2017)
• Page Start: 6613
• Page End: 6616
• Publication Date: 2017-06-05
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c7cc00846e
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Novel X-ray crystal structures of cyclicd /l peptide nanotubes in antiparallel and parallel configurations. Abstract : Nanotubes made from H-bonded cyclicd /l peptide (CP) subunits have great potential for the construction of nanomaterials of wide chemical and structural diversity but, to date, difficulties in structural characterisation have restricted development of these materials. We present the first crystal structures of continuous CP nanotubes with antiparallel and parallel stacking arrangements, assembled separately from two peptides; cyclo [(Asp-d -Leu-Lys-d -Leu)2 ] and cyclo [(Asp-d -Ala-Lys-d -Ala)2 ].