Electron-catalyzed radical perfluoroalkylation of organic sulfides: the serendipitous use of the TMEDA/I2 complex as a radical initiator. Issue 11 (9th May 2017)

• Record Type: Journal Article
• Authors: Yerien, D. E.; Barata-Vallejo, S.; Camps, B.; Cristófalo, A. E.; Cano, M. E.; Uhrig, M. L.; Postigo, A.
• Is Part Of: Catalysis science & technology. Volume 7:Issue 11(2017)
• Page Start: 2274
• Page End: 2282
• Publication Date: 2017-05-09
• Subjects: Catalysis -- Periodicals; 541.395
• DOI: 10.1039/c7cy00236j
• Languages: English
• ISSNs: 2044-4753

Abstract

Abstract : The (TMEDA)I·I3 complex as a new radical initiator for the perfluoroalkylation of RSH. Abstract : Radical initiation for the perfluoroalkylation reaction of sulfides has been performed using the complex [(TMEDA)I·I3 ] and visible light. This methodology bypasses the use of metal(organo)catalysts where the complex [(TMEDA)I·I3 ] acts as a good electron donor/reductant radical initiating agent. Biologically relevant sulfides are easily substituted with RF moieties employing a mild and environmentally benign radical strategy starting from readily available RF I.