Stenotrophomonas maltophilia in a university hospital of traditional Chinese medicine: molecular epidemiology and antimicrobial resistance. Issue 3 (July 2017)

• Record Type: Journal Article
• Authors: Zhao, S.; Yang, L.; Liu, H.; Gao, F.
• Is Part Of: Journal of hospital infection. Volume 96:Issue 3(2017)
• Page Start: 286
• Page End: 289
• Publication Date: 2017-07
• Subjects: Antibiotic resistance -- Stenotrophomonas maltophilia -- Molecular epidemiology; Cross infection -- Periodicals; Cross infection -- Prevention -- Periodicals; Nosocomial infections -- Periodicals; Nosocomial infections -- Prevention -- Periodicals; Cross Infection -- Periodicals; Cross Infection -- prevention & control -- Periodicals; Infection Control -- Periodicals; Electronic journals; 614.44
• DOI: 10.1016/j.jhin.2017.04.001
• Languages: English
• ISSNs: 0195-6701

Abstract

Summary: Stenotrophomona maltophilia has emerged as an important opportunistic pathogen that is highly antibiotic resistant. Analysis of antibiotic susceptibilities, drug-resistant gene profiles and molecular typing of S . maltophilia was undertaken in a university hospital of traditional Chinese medicine in East China. Resistance to sulphamethoxazole (SXT) was found to be an indicator of multi-drug resistance. SXT resistance was mediated by sul and dfrA genes in integrons, especially class 1. Some evidence of clonal dissemination was found, indicating the occurrence of cross-transmission of antibiotic-resistant strains within the hospital. This underscores the need for effective control and prevention measures in hospitals.