Nanoimprinted SERS Sensors for Chemical and Biological Detection. (16th January 2017)

• Record Type: Journal Article
• Authors: Strack, Guinevere; Fitzgerald, Michaela; Su, Junwei; Pelletier, Margery G. H.; Gaines, Peter; Sun, Hongwei; Kurup, Pradeep; Mosurkal, Ravi
• Is Part Of: MRS advances. Volume 2:Number 19/20(2017)
• Page Start: 1077
• Page End: 1082
• Publication Date: 2017-01-16
• Subjects: Raman spectroscopy, -- biological, -- sensor; Electrical engineering -- Congresses; Physics -- Congresses; Materials -- Research -- Congresses; Materials science -- Congresses; 620.11
• DOI: 10.1557/adv.2017.44
• Languages: English
• ISSNs: 2059-8521

Abstract

ABSTRACT: Herein, we demonstrate a facile, rapid, and scalable method to fabricate polymer-based gratings for surface-enhanced Raman spectroscopy (SERS) sensors. To accomplish this, epoxy nanostripe arrays on silicon substrates were prepared using thermal annealing and UV-cross-linking. After preparation of the nanostripe arrays, the surface was briefly treated with oxygen plasma, which decreased the surface energy and enabled the growth of AgNPs on the polymer surface using a simple, low-cost, aqueous-based synthesis procedure. The SERS substrates exhibited a detection limit of ∼1 pM using rhodamine 6G (R6G). In addition, preliminary work with E. coli DH5 showed that the nanoimprinted substrates can be used to obtain Raman spectra of washed bacteria cells.