Biocompatible fluorescent nano-apatite with ionic silver- Its antibacterial activity and cytotoxicity towards cancer cells. (2017)

• Record Type: Journal Article
• Authors: Asha, S.; Nimrodh Ananth, A.; Vanitha kumari, G.; Prakash, B.; Jose, Sujin P.; Jothi Rajan, M.A.
• Is Part Of: Materials today. Volume 4:Number 2(2017)Part C
• Page Start: 4309
• Page End: 4318
• Publication Date: 2017
• Subjects: Europium -- Luminescence -- Silver -- Antibacterial -- Cytotoxicity -- Biocompatibility; Materials science -- Congresses -- Periodicals; 620.1
• DOI: 10.1016/j.matpr.2017.04.001
• Languages: English
• ISSNs: 2214-7853

Abstract

Abstract: Europium doped hydroxyapatite (EDA) nanorods with various concentrations of ionic silver functionalized on its surface were prepared using a facile hydrothermal method. Enhancement and quenching in luminescence of europium was observed depending upon the concentration of silver ions. The antibacterial activity of the samples with various concentrations of silver was studied and it was observed that the antibacterial activity increased with increase in concentration of silver ions. These ionic silver functionalized EDA nanorods were found highly biocompatible to L929 fibroblast cells but were toxic to MCF-7 breast cancer cells indicating that these nanoparticles can be effectively used for theranostic applications.