Selective visualization of pelvic splanchnic nerve and pelvic plexus using readout-segmented echo-planar diffusion-weighted magnetic resonance neurography: A preliminary study in healthy male volunteers. Issue 86 (January 2017)

• Record Type: Journal Article
• Authors: Yamashita, Rikiya; Isoda, Hiroyoshi; Arizono, Shigeki; Furuta, Akihiro; Ohno, Tsuyoshi; Ono, Ayako; Murata, Katsutoshi; Togashi, Kaori
• Is Part Of: European journal of radiology. Issue 86(2017)
• Page Start: 52
• Page End: 57
• Publication Date: 2017-01
• Subjects: Magnetic resonance neurography -- Readout-segmented echo-planar diffusion-weighted imaging -- Pelvic autonomic innervation -- Pelvic splanchnic nerve -- Pelvic plexus -- Nerve-preserving surgery; Medical radiology -- Periodicals; Radiology -- Periodicals; Radiologie médicale -- Périodiques; Medical radiology; Periodicals; 616.075705
• DOI: 10.1016/j.ejrad.2016.10.034
• Languages: English
• ISSNs: 0720-048X

Abstract

Highlights: RS-EPI DW-MRN has a potential to selectively depict the pelvic parasympathetic nerve. The nervous visibility showed a moderate correlation with the image artifact level. Our method could help preserving function after pelvic nerve-preserving surgery. Abstract: Purpose: To evaluate the potential of readout-segmented echo-planar diffusion-weighted magnetic resonance neurography (RS-EPI DW-MRN) for the selective visualization of pelvic splanchnic nerve and pelvic plexus in healthy male volunteers. Materials and methods: Institutional review board approval and written informed consent were obtained. RS-EPI DW-MRN images were acquired from thirteen healthy male volunteers aged 25–48 years between September 2013 and December 2013. For RS-EPI DW-MRN, the following parameters were used: spatial resolution, 1.1 × 1.1 × 2.5 mm; b -value, 250 s/mm 2 ; number of readout-segments, seven; and acquisition time, 7 min 45 s. For qualitative assessment, two abdominal radiologists independently evaluated the visibility of the pelvic splanchnic nerves and pelvic plexuses bilaterally in each subject on oblique coronal thin-slab 10-mm-thick maximum intensity projection images and scored it with a 4-point grading scale (excellent, good, fair, poor). Both readers scored twice at 6-month intervals. Inter-observer and intra-observer variability were evaluated using Cohen's quadratically weighted κ statistics. Image artifact level was scored on a 4-point grading scale by other two abdominal radiologists in order to evaluate the correlation between the nerve visibility and the severity of imaging artifacts using the Spearman's correlation coefficient. Results: Qualitative grading showed the following success rate (number of nerves qualitatively scored as excellent or good divided by total number of nerves): reader 1 (first set), 73% (19/26); reader 2 (first set), 77% (20/26); reader 1 (second set), 81% (21/26); and reader 2 (second set), 77% (20/26). Inter-observer agreement between readers 1 and 2 was excellent: κ = 0.947 (first set) and 0.845 (second set). Intra-observer agreement was also excellent: κ = 0.810 (reader 1) and 0.946 (reader 2). The visibility of pelvic splanchnic nerve and pelvic plexus showed a moderate correlation with the image artifact level (ρ = 0.54, p = 0.004). Conclusion: This study demonstrated that RS-EPI DW-MRN is a promising approach for selectively visualizing the pelvic splanchnic nerve and pelvic plexus.