Adsorption of diclofenac and nimesulide on activated carbon: Statistical physics modeling and effect of adsorbate size. (October 2017)

• Record Type: Journal Article
• Authors: Sellaoui, Lotfi; Mechi, Nesrine; Lima, Éder Cláudio; Dotto, Guilherme Luiz; Ben Lamine, Abdelmottaleb
• Is Part Of: Journal of physics and chemistry of solids. Volume 109(2017)
• Page Start: 117
• Page End: 123
• Publication Date: 2017-10
• Subjects: Adsorption -- Modeling -- Activated carbon -- Pharmaceutical molecules; Solids -- Periodicals; Solides -- Périodiques; Solids; Periodicals; 530.41
• DOI: 10.1016/j.jpcs.2017.05.019
• Languages: English
• ISSNs: 0022-3697

Abstract

Abstract: Based on statistical physics elements, the equilibrium adsorption of diclofenac (DFC) and nimesulide (NM) on activated carbon was analyzed by a multilayer model with saturation. The paper aimed to describe experimentally and theoretically the adsorption process and study the effect of adsorbate size using the model parameters. From numerical simulation, the number of molecules per site showed that the adsorbate molecules (DFC and NM) were mostly anchored in both sides of the pore walls. The receptor sites density increase suggested that additional sites appeared during the process, to participate in DFC and NM adsorption. The description of the adsorption energy behavior indicated that the process was physisorption. Finally, by a model parameters correlation, the size effect of the adsorbate was deduced indicating that the molecule dimension has a negligible effect on the DFC and NM adsorption. Highlights: Modeling of adsorption isotherms of diclofenac and nimesulide on activated carbon. Size effect study of the adsorbate molecule using the statistical physics model parameters. Development of steric interpretations.