Antibacterial activity of N-halamine decorated mesoporous silica nanoparticles. (September 2017)

• Record Type: Journal Article
• Authors: Xu, Jiarong; Zhang, Yu; Zhao, Yanbao; Zou, Xueyan
• Is Part Of: Journal of physics and chemistry of solids. Volume 108(2017)
• Page Start: 21
• Page End: 24
• Publication Date: 2017-09
• Subjects: N-halamine -- Nanoparticles -- Porous materials -- Antibacterial activity; Solids -- Periodicals; Solides -- Périodiques; Solids; Periodicals; 530.41
• DOI: 10.1016/j.jpcs.2017.04.008
• Languages: English
• ISSNs: 0022-3697

Abstract

Abstract: N-halamine decorated mesoporous silica nanoparticles (mSiO2 /halamine NPs) were prepared by coating mSiO2 NPs with poly (1-allylhydantoin-co-methyl methacrylate) (AH-co-MMA) by the aid of the radical polymerization, followed by chlorination treatment. The sterilizing effect on the bacterial strain is investigated by incubating Staphylococcus aureus ( S. aureus ) and Escherichia coli ( E. coli ). Results indicated that the mSiO2 /halamine NPs had excellent antibacterial activity and no significant change occurred in antibacterial efficiency after five recycle experiments. Highlights: Allylhydantoin based polymer was prepared by polymerization. N-halamine antimicrobial agent was obtained by chlorination. mSiO2 /halamine NPs displayed excellent antibacterial activity.