Titanium dioxide nanotubes addition to self-adhesive resin cement: Effect on physical and biological properties. Issue 7 (July 2017)

• Record Type: Journal Article
• Authors: Ramos-Tonello, Carla M.; Lisboa-Filho, Paulo N.; Arruda, Larisa B.; Tokuhara, Cintia K.; Oliveira, Rodrigo C.; Furuse, Adilson Y.; Rubo, José H.; Borges, Ana Flávia S.
• Is Part Of: Dental materials. Volume 33:Issue 7(2017)
• Page Start: 866
• Page End: 875
• Publication Date: 2017-07
• Subjects: Dental cements -- Polymerization -- Nanotechnology -- Nanotubes -- Titanium -- Physical and chemical properties -- Mechanical phenomena; Dentistry -- Periodicals; Dental materials -- Periodicals; 617.695
• DOI: 10.1016/j.dental.2017.04.022
• Languages: English
• ISSNs: 0109-5641

Abstract

Highlights: The presence of monomers with acidic groups in self-adhesive resin cements allows a simplified indirect luting technique. ​The same acidic monomers may adversely affect their properties where the passage of light is inefficient or absent. The incorporation of nanostructures into dental polymers has shown promising results. Abstract: Objectives: This study has investigated the influence of Titanium dioxide nanotubes (TiO2 -nt) addition to self-adhesive resin cement on the degree of conversion, water sorption, and water solubility, mechanical and biological properties. Methods: A commercially available auto-adhesive resin cement (RelyX U200™, 3M ESPE) was reinforced with varying amounts of nanotubes (0.3, 0.6, 0.9 wt%) and evaluated at different curing modes (self- and dual cure). The DC in different times (3, 6, 9, 12 and 15 min), water sorption (Ws) and solubility (Sl), 3-point flexural strength ( σf ), elastic modulus (E), Knoop microhardness (H) and viability of NIH/3T3 fibroblasts were performed to characterize the resin cement. Results: Reinforced self-adhesive resin cement, regardless of concentration, increased the DC for the self- and dual-curing modes at all times studied. The concentration of the TiO2 -nt and the curing mode did not influence the Ws and Sl. Regarding σf, concentrations of both 0.3 and 0.9 wt% for self-curing mode resulted in data similar to that of dual-curing unreinforced cement. The E increased with the addition of 0.9 wt% for self-cure mode and H increased with 0.6 and 0.9 wt% for both curing modes. Cytotoxicity assays revealed that reinforced cements were biocompatible. Significance: TiO2 -nt reinforced self-adhesive resin cement are promising materials for use in indirect dental restorations. Taken together, self-adhesive resin cement reinforced with TiO2 -nt exhibited physicochemical and mechanical properties superior to those of unreinforced cements, without compromising their cellular viability.