Early-stage Favourable Anal Cancer: A Retrospective Analysis of Clinical Outcomes of a Moderately Low Dose Elective Nodal Intensity-modulated Radiotherapy Schedule. Issue 7 (July 2017)

• Record Type: Journal Article
• Authors: Lestrade, L.; Zilli, T.; Kountouri, M.; Jumeau, R.; Matzinger, O.; Bourhis, J.; Miralbell, R.; Ozsahin, M.; De Bari, B.
• Is Part Of: Clinical oncology. Volume 29:Issue 7(2017)
• Page Start: e105
• Page End: e109
• Publication Date: 2017-07
• Subjects: Anal cancer -- early-stage -- IMRT -- local control -- radiotherapy -- toxicity; Oncology -- Periodicals; Tumors -- Periodicals; Cancer -- Treatment -- Periodicals; Radiotherapy -- Periodicals; Neoplasms -- Periodicals; Cancer -- Radiotherapy; Cancer -- Treatment; Oncology; Medical radiology; Radiotherapy; Tumors; Electronic journals; Periodicals; 616.994
• DOI: 10.1016/j.clon.2017.01.044
• Languages: English
• ISSNs: 0936-6555

Abstract

Abstract: In this retrospective study we evaluated the long-term results of 35 early-stage favourable T1-2 N0 M0 anal cancer patients treated with intensity-modulated radiotherapy techniques combining low dose prophylactic inguinal-pelvic irradiation with dose-escalated boost. Optimal locoregional control and good tolerance makes this treatment a valuable alternative to brachytherapy boost and involved-field radiotherapy plans. Highlights: We evaluated 35 early-stage favourable T1-2 N0 M0 anal cancer patients. Treatment consisted of low dose inguinal-pelvic intensity-modulated radiotherapy with a dose-escalated boost. Optimal locoregional control and good tolerance were observed. This treatment may be an alternative to brachytherapy boost and involved-field radiotherapy.