Efficacy of black cohosh (Cimicifuga racemosa) medicines for treatment of menopausal symptoms – comments on major statements of the Cochrane Collaboration report 2012 "black cohosh (Cimicifuga spp.) for menopausal symptoms (review)". (2nd September 2013)

• Record Type: Journal Article
• Authors: Beer, André-M.; Osmers, Rüdiger; Schnitker, Jörg; Bai, Wenpei; Mueck, Alfred O.; Meden, Harald
• Is Part Of: Gynecological endocrinology. Volume 29:Number 12(2013:Dec.)
• Page Start: 1022
• Page End: 1025
• Publication Date: 2013-09-02
• Subjects: Actaea – Cimicifuga racemosa -- benefit-risk ratio -- black cohosh -- clinical studies -- Cochrane report -- menopausal symptoms; Endocrine gynecology -- Periodicals; Generative organs, Female -- Diseases -- Periodicals; 618.1
• DOI: 10.3109/09513590.2013.831836
• Languages: English
• ISSNs: 0951-3590

Abstract

Abstract: Menopausal symptoms management with high-quality plant extracts from Actaea ( Cimicifuga. racemosa rootstock is well-established. Efficacy and safety are supported by research and clinical trials since several decades and backed up by official monographs. However, the recent published Cochrane review on black cohosh neglects major evidence for beneficial effects. The authors' negative conclusions are questionable and call for reply and clarification. Our careful reconsideration of all appropriate placebo-controlled clinical studies reveals a standardized mean difference of 0.385 in favor of black cohosh ( p < 0.0001).