Biodegradation of naproxen by freshwater algae Cymbella sp. and Scenedesmus quadricauda and the comparative toxicity. (August 2017)

• Record Type: Journal Article
• Authors: Ding, Tengda; Lin, Kunde; Yang, Bo; Yang, Mengting; Li, Juying; Li, Wenying; Gan, Jay
• Is Part Of: Bioresource technology. Volume 238(2017)
• Page Start: 164
• Page End: 173
• Publication Date: 2017-08
• Subjects: Naproxen -- Biodegradation -- Degradation pathway -- Algae -- Toxicity; Biomass -- Periodicals; Biomass energy -- Periodicals; Bioremediation -- Periodicals; Agricultural wastes -- Periodicals; Factory and trade waste -- Periodicals; Organic wastes -- Periodicals; Bioénergie -- Périodiques; Déchets agricoles -- Périodiques; Déchets industriels -- Périodiques; Déchets organiques -- Périodiques; Déchets (Combustible) -- Périodiques; 662.88
• DOI: 10.1016/j.biortech.2017.04.018
• Languages: English
• ISSNs: 0960-8524

Abstract

Graphical abstract: Highlights: Cymbella sp. and S. quadricauda were completely inhibited at 100 ppm naproxen. Cymbella sp. showed a more satisfactive effect in the bioremediation of naproxen. Naproxen affected biochemical characteristics of both algae. Naproxen degradation mechanisms are proposed based on 12 identified metabolites. Abstract: Naproxen is one of the most prevalent pharmaceuticals and of great environment concern. Information about bioremediation of naproxen by algae remains limited and no study has been reported on the degradation mechanism and the toxicity of NPX on algae. In this study, both Cymbella sp. and Scenedesmus quadricauda showed complete growth inhibition (100%) at 100 mg L −1 within 24 h. Biochemical characteristics including chlorophyll a, carotenoid contents and enzyme activities for these two microalgae were affected by NPX at relatively high concentrations after 4 d of exposure. Degradation of naproxen was accelerated by both algae species. Cymbella sp. showed a more satisfactive effect in the bioremediation of NPX with higher removal efficiency. A total of 12 metabolites were identified by LC-MS/MS and the degradation pathways of naproxen in two algae were proposed. Hydroxylation, decarboxylation, demethylation, tyrosine conjunction and glucuronidation contributed to naproxen transformation in algal cells.