Deep eutectic solvents as green media for efficient extraction of terpene trilactones from Ginkgo biloba leaves. Issue 8 (9th May 2017)

• Record Type: Journal Article
• Authors: Su, Erzheng; Yang, Meng; Cao, Jun; Lu, Chao; Wang, Jiahong; Cao, Fuliang
• Is Part Of: Journal of liquid chromatography & related technologies. Volume 40:Issue 8(2017)
• Page Start: 385
• Page End: 391
• Publication Date: 2017-05-09
• Subjects: Deep eutectic solvents -- Ginkgo biloba -- green solvent -- recovery -- terpene trilactones -- ultrasound-assisted extraction; Liquid chromatography -- Periodicals; Chromatographic analysis -- Periodicals; Separation (Technology) -- Periodicals; Biotechnology -- Periodicals; Chromatography, Liquid -- Periodicals; 543.8405
• DOI: 10.1080/10826076.2017.1309661
• Languages: English
• ISSNs: 1082-6076

Abstract

ABSTRACT: Deep eutectic solvents (DESs)-based ultrasonic extraction of terpene trilactones (TTLs) from Ginkgo biloba leaves was efficiently developed. Sixteen DESs were prepared, and DESs composed of choline chloride-urea (ChCl-U) and betaine-ethylene glycol (BE-EG) gave higher TTL extraction yields than the present, most efficient solvent 70% ethanol. The extraction conditions were further optimized, and the optimum conditions were as follows: taking BE-EG containing 40% (w/w) water as the extraction solvent, 1:10 of G. biloba leaves powder-to-solvent ratio, and ultrasonic treatment at 45°C and 100 W for 20 min. A total extraction yield of 1.94 ± 0.03 mg/g was obtained under the optimum conditions, which indicated that 99.37% of TTLs could be extracted from the G. biloba leaves powder by a single extraction. Moreover, the polyamide resin was used to recover the TTLs in DES extracting solution, and recovery yield of 95.1% was attained. Therefore, BE-EG containing 40% (w/w) water was a potential alternative solvent for TTLs extraction from G. biloba leaves. GRAPHICAL ABSTRACT: