Semisynthesis of esters and oxime esters/sulfonates from furyl-ring-based acetylation derivatives of fraxinellone as insecticidal agents. Issue 45 (26th May 2017)

• Record Type: Journal Article
• Authors: Guo, Yong; Yang, Ruige; Xu, Hui
• Is Part Of: RSC advances. Volume 7:Issue 45(2017)
• Page Start: 28009
• Page End: 28015
• Publication Date: 2017-05-26
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c7ra03588h
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Two compounds9a and10i exhibited the most promising pesticidal activity against early 3rd-instar larvae of Mythimna separata . Their structure–activity relationships were also observed. Abstract : In continuation of our program to discover new natural-product-based crop protection agents, we prepared a series of esters and oxime esters/sulfonates from furyl-ring-based acetylation derivatives as pesticidal agents by structural modification of fraxinellone, a biorenewable degraded limonoid isolated from Meliaceae and Rutaceae plants. The structural assignment was based on the spectroscopic and X-ray analysis data. Their insecticidal activity was evaluated against a crop-threatening agricultural insect pest, Mythimna separata Walker. Among all derivatives, compounds9a and10i exhibited the most promising pesticidal activity. Their structure–activity relationships were also discussed.