A novel metal-free method for the selenocyanation of aromatic ketones to afford α-carbonyl selenocyanates. Issue 20 (10th May 2017)

• Record Type: Journal Article
• Authors: Sun, Kai; Lv, Yunhe; Chen, Yao; Zhou, Tingting; Xing, Yanyan; Wang, Xin
• Is Part Of: Organic & biomolecular chemistry. Volume 15:Issue 20(2017)
• Page Start: 4464
• Page End: 4467
• Publication Date: 2017-05-10
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c7ob00958e
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A rapid access to α-carbonyl selenocyanates has been developed through the direct selenocyanation of aromatic ketones. Abstract : A new method has been developed for the selenocyanation of aromatic ketones. This reaction avoids the need to use pre-prepared α-halo ketones, providing rapid access to α-carbonyl selenocyanates. We also investigated the mechanism for this reaction and found that it proceeds via sequential radical iodination and nucleophilic substitution reactions.