Hematological disorders at birth in complicated monochorionic twins. Issue 6 (3rd June 2017)

• Record Type: Journal Article
• Authors: Verbeek, Lianne; Slaghekke, Femke; Sueters, Marieke; Middeldorp, Johanna M.; Klumper, Frans J.; Haak, Monique C.; Oepkes, Dick; Lopriore, Enrico
• Is Part Of: Expert review of hematology. Volume 10:Issue 6(2017)
• Page Start: 525
• Page End: 532
• Publication Date: 2017-06-03
• Subjects: Monochorionic twins -- twin-twin transfusion syndrome -- twin anemia-polycythemia sequence -- anemia -- thrombocytopenia -- polycythemia -- blood transfusion -- partial exchange transfusion; Hematology -- Periodicals; 616.15005
• DOI: 10.1080/17474086.2017.1324290
• Languages: English
• ISSNs: 1747-4086

Abstract

ABSTRACT: Introduction : Monochorionic twins are at risk of severe complications including twin-twin transfusion syndrome (TTTS), twin anemia-polycythemia sequence (TAPS) and acute peripartum TTTS. The pathophysiology is based on inter-twin blood transfusion through placental vascular anastomoses. Areas covered : This review focuses on the incidence, management and outcome of neonatal hematological complications at birth in TTTS, TAPS and acute peripartum TTTS. Expert commentary : Hematological disorders are often present at birth in monochorionic twins and include acute or chronic anemia, polycythemia and thrombocytopenia. Routine measurement of complete blood counts in all complicated monochorionic twins is strongly recommended. Increased awareness on these disorders and correct diagnostic tests will lead to prompt and adequate management at birth.