Sonochemical synthesis and stabilization of concentrated antimicrobial silver‐chitosan nanoparticle dispersions. Issue 30 (2nd April 2017)

• Record Type: Journal Article
• Authors: Francesko, Antonio; Cano Fossas, Marta; Petkova, Petya; Fernandes, Margarida M.; Mendoza, Ernest; Tzanov, Tzanko
• Is Part Of: Journal of applied polymer science. Volume 134:Issue 30(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-04-02
• Subjects: composites -- manufacturing -- nanocrystals -- nanoparticles -- nanowires -- synthesis and processing techniques; Polymers -- Periodicals; Polymerization -- Periodicals; 668.9
• DOI: 10.1002/app.45136
• Languages: English
• ISSNs: 0021-8995

Abstract

ABSTRACT: This work reports on a green synthetic route to produce concentrated aqueous dispersions of silver nanoparticles (AgNP) employing high‐intensity ultrasound (US) and chitosan (CS) as a nontoxic reducing agent for Ag + salts and AgNP stabilizer. The sonication simultaneously boosted the synthesis and improved the stability of the AgNP, capping them with CS. Hybrid AgNP‐CS antimicrobial dispersions, stable for at least 6 months, were synthesized in a simple single step process. The use of US allowed for applying relatively mild processing temperatures (60 °C) and reaction time between 30 min and 3 h to obtain concentrated dispersions of AgNP that otherwise could not be obtained even after 72 h under mechanical stirring at the same reaction conditions. Upon sonication spherical AgNP‐CS with a size between 60 and 100 nm were generated, in contrast to the average diameter of ∼200 nm of the particles obtained by stirring. The antibacterial efficiency of the AgNP‐CS hybrids was evaluated against the medically relevant pathogens Staphylococcus aureus and Escherichia coli . The US‐synthesized AgNP‐CS showed more than three fold higher antibacterial activity compared to the particles obtained under stirring, due to their higher concentration and smaller size. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2017, 134, 45136. Abstract :