Classical and non-classical causes of GH deficiency in adults. Issue 1 (February 2017)

• Record Type: Journal Article
• Authors: Tanriverdi, F.; Kelestimur, F.
• Is Part Of: Best practice & research. Volume 31:Issue 1(2017)
• Page Start: 3
• Page End: 11
• Publication Date: 2017-02
• Subjects: growth hormone deficiency -- hypopituitarism -- traumatic brain injury -- sports-related head trauma -- Sheehan's syndrome; Endocrine glands -- Diseases -- Periodicals; Metabolism -- Disorders -- Periodicals; Endocrinology -- Periodicals; Metabolism -- Periodicals; 616.4
• DOI: 10.1016/j.beem.2017.02.001
• Languages: English
• ISSNs: 1521-690X

Abstract

Abstract : Growth hormone deficiency (GHD) can develop due to a variety of conditions, and may occur either as isolated or multiple pituitary hormone deficiencies. It has been previously demonstrated that GH is one of the most frequent hormonal deficiencies in adult patients with hypopituitarism. The most frequent classical causes of adult-onset GHD (AO-GHD) are pituitary adenomas and/or their treatment. However, during the last decade an increasing number of studies from different parts of the world have revealed that non-tumoural causes of hypopituitarism are more common than previously known. Therefore, in this review our aim is to briefly summarize the classical and non-classical acquired causes of GHD in adults.