Stereotactic body radiotherapy for pediatric hepatocellular carcinoma with central biliary obstruction. Issue 6 (5th November 2016)

• Record Type: Journal Article
• Authors: Hiniker, Susan M.; Rangaswami, Arun; Lungren, Matthew P.; Thakor, Avnesh S.; Concepcion, Waldo; Balazy, Kathleen E.; Kovalchuk, Nataliya; Donaldson, Sarah S.
• Is Part Of: Pediatric blood & cancer. Volume 64:Issue 6(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2016-11-05
• Subjects: HCC -- hepatocellular carcinoma -- SBRT -- stereotactic body radiotherapy; Tumors in children -- Periodicals; Blood -- Diseases -- Periodicals; Cancer in children -- Periodicals; 618.92
• DOI: 10.1002/pbc.26330
• Languages: English
• ISSNs: 1545-5009

Abstract

Abstract: Here, we present the case of a pediatric patient with newly diagnosed hepatocellular carcinoma causing central biliary obstruction and persistently elevated bilirubin of 3.0–4.3 mg/dl despite placement of bilateral internal–external biliary drains. The tumor was not resectable, and the patient was not a candidate for liver transplant due to nodal disease, for chemotherapy due to hyperbilirubinemia, or for local therapies aside from stereotactic body radiotherapy (SBRT). In this report, we discuss the successful use of SBRT in the management of this patient, and its role in allowing the patient to become a candidate for additional therapies.