Hemophagocytic Lymphohistiocytosis in a Newborn Presenting as "Blueberry Muffin Baby". Issue 3 (May 2017)

• Record Type: Journal Article
• Authors: Larson, Krista N.; Gaitan, Sergio R.; Stahr, Benjamin J.; Morrell, Dean S.
• Is Part Of: Pediatric dermatology. Volume 34:Issue 3(2017:May/Jun.)
• Page Start: e150
• Page End: e151
• Publication Date: 2017-05
• Subjects: Pediatric dermatology -- Periodicals; Children -- Diseases -- Periodicals; 618.925
• DOI: 10.1111/pde.13128
• Languages: English
• ISSNs: 0736-8046

Abstract

Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a rare, life‐threatening hyperinflammatory syndrome characterized by uncontrolled activation and proliferation of proinflammatory cytokines. Initial presentation commonly includes fever, hepatosplenomegaly, and pancytopenia; 6 to 65% of cases also have a concurrent cutaneous eruption. We present the case of a 6‐day‐old premature infant boy with congenital severe thrombocytopenia, anemia, and hepatosplenomegaly who presented with several cutaneous violaceous papules and nodules and was found to have HLH.