Successful Renal Transplantation in Small Children With a Completely Thrombosed Inferior Vena Cava. Issue 6 (28th February 2017)

• Record Type: Journal Article
• Authors: Verghese, P.; Minja, E.; Kirchner, V.; Chavers, B.; Matas, A.; Chinnakotla, S.
• Is Part Of: American journal of transplantation. Volume 17:Issue 6(2017)
• Page Start: 1670
• Page End: 1673
• Publication Date: 2017-02-28
• Subjects: clinical research/practice -- kidney transplantation/nephrology -- kidney transplantation: living donor -- complication: surgical/technical; Transplantation of organs, tissues, etc -- Periodicals; 617.95
• DOI: 10.1111/ajt.14213
• Languages: English
• ISSNs: 1600-6135

Abstract

Abstract : In small children with end‐stage renal disease, an adult‐sized kidney transplant is the best option. However, in the face of a completely thrombosed inferior vena cava (IVC), such transplants can be challenging, given the difficulty of achieving adequate renal venous outflow and the risk of graft thrombosis. Using a new technique to anastomose the renal vein to the right hepatic vein/IVC junction, we successfully implanted an adult‐sized graft in two small children (9.8 and 14 kg) who had end‐stage renal disease and a completely thrombosed IVC. After mobilizing the right lobe of the liver and obtaining total vascular occlusion of the liver, we used a Fogarty catheter to dilate the retrohepatic IVC. In the right hepatic vein, we made a venotomy and extended it inferiorly onto the retrohepatic IVC. To that venotomy, we anastomosed the donor left renal vein, using continuous 7‐0 Prolene sutures. Both patients attained excellent renal allograft function: One had a serum creatinine level of 0.30 mg/dL at 6 mo after transplant, and the other had a level of 0.29 mg/dL at 1 year. In these two small children with completely thrombosed IVC, our technique for transplanting an adult‐sized kidney provided adequate venous outflow. Abstract : Using a new technique to anastomose the renal vein to the right hepatic vein/inferior vena cava junction, small children with a completely thrombosed inferior cava can be successfully transplanted.