A dynamic invertible intramolecular charge-transfer fluorescence probe: real-time monitoring of mitochondrial ATPase activity12. Issue 40 (3rd May 2017)

• Record Type: Journal Article
• Authors: Zhang, Hua; Wang, Yafu; Xuan, Xiaopeng; Wang, Ge; Guo, Haiming; Fan, Jiangli
• Is Part Of: Chemical communications. Volume 53:Issue 40(2017)
• Page Start: 5535
• Page End: 5538
• Publication Date: 2017-05-03
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c7cc02450a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A dynamic invertible intramolecular charge-transfer fluorescence probe was successfully utilized for the real-time monitoring of mitochondrial ATPase activity. Abstract : A dynamic invertible intramolecular charge-transfer (ICT) process could provide abundant response signals for real-time monitoring in living organisms. Herein, based on dynamic invertible ICT, we have reported a cancer cell-targeted fluorescence probe (OPM ) for mitochondrial ATPase activity. Due to its abundant response signals, OPM could real-time monitor mitochondrial ATPase activity during the cancer apoptosis process, successfully.