Back Cover: Luminescent Metal–Organic‐Framework‐Based Label‐Free Assay of Polyphenol Oxidase with Fluorescent Scan (Chem. Eur. J. 27/2017). Issue 27 (15th March 2017)

• Record Type: Journal Article
• Authors: Li, Yue; Guo, An; Chang, Lan; Li, Wen‐Juan; Ruan, Wen‐Juan
• Is Part Of: Chemistry. Volume 23:Issue 27(2017)
• Page Start: 6702
• Page End: 6702
• Publication Date: 2017-03-15
• Subjects: enzyme assay -- fluorescence -- metal-organic frameworks -- polyphenol oxidase -- sensors; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201700764
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract : A MOF‐based label‐free enzyme assay was designed in this work. To analyze polyphenol oxidase (PPO) activity, a luminescent MOF in which the emission could be selectively quenched by the o ‐quinone product was synthesized. With it, the kinetics of PPO‐catalyzed oxidation could be reflected with the fluorescence signal. This method exhibits the advantages of high sensitivity, wide substrate adaptability, and minimal effects on the enzymatic reaction. More information can be found in the Full Paper by W.‐J. Ruan, et al. onpage 6562 ff.