Breast cancers detected in only one of two arms of a tomosynthesis (3D-mammography) population screening trial (STORM-2). (April 2017)

• Record Type: Journal Article
• Authors: Bernardi, Daniela; Houssami, Nehmat
• Is Part Of: Breast. Volume 32(2017)
• Page Start: 98
• Page End: 101
• Publication Date: 2017-04
• Subjects: Digital breast tomosynthesis -- Mammography -- Population screening; Breast -- Diseases -- Periodicals; Breast -- Tumors -- Periodicals; Breast -- Periodicals; Electronic journals; Periodicals; 616
• DOI: 10.1016/j.breast.2017.01.005
• Languages: English
• ISSNs: 0960-9776

Abstract

Abstract: The prospective ' s creening with t omosynthesis or standard m ammography-2 (STORM-2)' trial compared mammography screen-reading strategies and showed that each of integrated 2D/3D-mammography or 2Dsynthetic/3D-mammography detected significantly more breast cancers than 2D-mammography alone. This short report describes 13 (from 90) cancers detected in only one of two parallel double-reading arms implemented in STORM-2. Amongst this subset of cases, the majority was invasive cancer ≤16 mm, mostly depicted as irregular masses or distortions. Furthermore, most were detected at 3D-mammography only and predominantly by one reader from double-reading pairs, highlighting that 3D-mammography may enable detection of cancers that are challenging to perceive at routine screening. Highlights: 13 from 90 cancers were detected in only one of two double-reading arms of a screening trial. Amongst this subset of breast cancers, most were invasive cancers ≤16 mm. The majority of these cases were depicted as irregular masses or distortions. Most of these 13 cancers were detected at 3D-mammography only. Most of these cancers were detected by only one reader from double-reading pairs.