A teaching approach from the exhaustive search method to the Needleman–Wunsch algorithm. Issue 3 (14th October 2016)

• Record Type: Journal Article
• Authors: Xu, Zhongneng; Yang, Yayun; Huang, Beibei
• Is Part Of: Biochemistry and molecular biology education. Volume 45:Issue 3(2017)
• Page Start: 194
• Page End: 204
• Publication Date: 2016-10-14
• Subjects: Needleman–Wunsch algorithm -- exhaustive search -- sequence alignment -- teaching; Biochemistry -- Study and teaching -- Periodicals; Molecular biology -- Study and teaching -- Periodicals; 572.071
• DOI: 10.1002/bmb.21027
• Languages: English
• ISSNs: 1470-8175

Abstract

Abstract: The Needleman–Wunsch algorithm has become one of the core algorithms in bioinformatics; however, this programming requires more suitable explanations for students with different major backgrounds. In supposing sample sequences and using a simple store system, the connection between the exhaustive search method and the Needleman–Wunsch algorithm was analyzed to more thoroughly explain this algorithm. The present study could benefit the teaching and learning of the Needleman–Wunsch algorithm. © 2016 by The International Union of Biochemistry and Molecular Biology, 45(3):194–204, 2017.