Zygote intrafallopian transfer among patients with repeated implantation failure. Issue 1 (11th October 2012)

• Record Type: Journal Article
• Authors: Weissman, Ariel; Horowitz, Eran; Ravhon, Amir; Nahum, Hana; Golan, Abraham; Levran, David
• Is Part Of: International journal of gynaecology and obstetrics. Volume 120:Issue 1(2013)
• Page Start: 70
• Page End: 73
• Publication Date: 2012-10-11
• Subjects: In vitro fertilization‐embryo transfer -- Repeated implantation failure -- Zygote intrafallopian transfer; Gynecology -- Periodicals; Obstetrics -- Periodicals; Electronic journals; 618
• DOI: 10.1016/j.ijgo.2012.07.018
• Languages: English
• ISSNs: 0020-7292

Abstract

Abstract: Objective: To summarize the experience of a single center with laparoscopic zygote intrafallopian transfer (ZIFT) performed exclusively among patients with high‐order repeated implantation failure (RIF) following in vitro fertilization‐embryo transfer (IVF‐ET). Methods: A retrospective cohort study was performed at the Edith Wolfson Medical Center, a tertiary referral university hospital located in Holon, Israel. A group of 176 patients with 8.15 ± 3.9 previously failed IVF‐ET cycles underwent 280 ZIFT procedures between 1995 and 2010. The main outcome measure was the live birth rate per patient treated. Results: In all, there were 274 fresh and 6 frozen ZIFT cycles recorded in the study cohort, resulting in 96 clinical pregnancies per attempt (34.3%) and 72 live births (25.7%). The live birth rate per patient was 39.8%. Conclusion: The use of ZIFT remains a powerful tool in the clinical management of selected patients with high‐order RIF. This procedure should be kept in mind when all other measures fail among patients with at least 1 unobstructed fallopian tube.