Exacerbation phenotyping in chronic obstructive pulmonary disease. Issue 5 (28th October 2013)

• Record Type: Journal Article
• Authors: MacDonald, Martin; Korman, Tony; King, Paul; Hamza, Kais; Bardin, Philip
• Is Part Of: Significance. Volume 10:Issue 5(2013:Dec.)
• Page Start: 1280
• Page End: 1281
• Publication Date: 2013-10-28
• Subjects: clinical respiratory medicine -- chronic obstructive pulmonary disease -- emphysema -- infection and inflammation -- viral infection; Statistics -- Periodicals; Social sciences -- Periodicals; 001.422
• DOI: 10.1111/resp.12197
• Languages: English
• ISSNs: 1740-9705

Abstract

Abstract : Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are crucial events but causes remain poorly defined. A method to clinically 'phenotype' AECOPD have been proposed, and 52 hospitalized chronic obstructive pulmonary disease exacerbations according to underlying aetiology have now been prospectively phenotyped. Multiple exacerbation phenotypes were identified. A subpopulation coinfected with virus and bacteria had a significantly longer length of hospital stay, and this pilot study indicates that exacerbation phenotyping may be advantageous.