Thiourea catalysed reduction of α-keto substituted acrylate compounds using Hantzsch ester as a reducing agent in water. Issue 37 (26th April 2017)

• Record Type: Journal Article
• Authors: Weng, Guanglin; Ma, Xiaobo; Fang, Dongmei; Tan, Ping; Wang, Lijiao; Yang, Linlin; Zhang, Yuanyuan; Qian, Shan; Wang, Zhouyu
• Is Part Of: RSC advances. Volume 7:Issue 37(2017)
• Page Start: 22909
• Page End: 22912
• Publication Date: 2017-04-26
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c7ra00995j
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : The first method for the reduction of α-keto substituted acrylate compounds by Hantzsch ester in water under the catalysis of thiourea has been developed. The products were isolated with moderate to high yields (38–95%). Abstract : The first method for the reduction of α-keto substituted acrylate compounds by Hantzsch ester in water under the catalysis of thiourea has been developed. The products were isolated in moderate to high yields (38–95%). These products are important intermediates in the synthesis of a series of natural products and other biologically active molecules.