Foscarnet calcium microcrystals as the intravitreal drug depot. Issue 37 (24th April 2017)
- Record Type:
- Journal Article
- Title:
- Foscarnet calcium microcrystals as the intravitreal drug depot. Issue 37 (24th April 2017)
- Main Title:
- Foscarnet calcium microcrystals as the intravitreal drug depot
- Authors:
- Sun, Yuling
Tao, Yong
Cao, Qingchen
Huang, Yanbin - Abstract:
- Abstract : Injectable foscarnet calcium microcrystals can maintain the intravitreal drug concentration for months. Abstract : Foscarnet sodium is an antiviral drug for the treatment of CMV retinitis, currently in the form of twice-weekly intravitreal injection. Here we developed foscarnet calcium microcrystals as the drug depot, and using the rabbit model we demonstrated that the injected microcrystals maintained a therapeutically relevant drug concentration in the vitreous for more than 3 months.
- Is Part Of:
- Chemical communications. Volume 53:Issue 37(2017)
- Journal:
- Chemical communications
- Issue:
- Volume 53:Issue 37(2017)
- Issue Display:
- Volume 53, Issue 37 (2017)
- Year:
- 2017
- Volume:
- 53
- Issue:
- 37
- Issue Sort Value:
- 2017-0053-0037-0000
- Page Start:
- 5139
- Page End:
- 5142
- Publication Date:
- 2017-04-24
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c7cc02399e ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 39.xml