A two-photon fluorescent probe for specific detection of hydrogen sulfide based on a familiar ESIPT fluorophore bearing AIE characteristics12. Issue 35 (13th April 2017)

• Record Type: Journal Article
• Authors: Chen, Liyan; Wu, Di; Lim, Chang Su; Kim, Dayoung; Nam, Sang-Jip; Lee, Woolin; Kim, Gyungmi; Kim, Hwan Myung; Yoon, Juyoung
• Is Part Of: Chemical communications. Volume 53:Issue 35(2017)
• Page Start: 4791
• Page End: 4794
• Publication Date: 2017-04-13
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c7cc01695f
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A two-photon fluorescent probe based on an ESIPT fluorophore bearing AIE characteristics was utilized to detect H2 S. Abstract : Hydrogen sulfide (H2 S) is a signaling gasotransmitter, which plays various roles in modulating the functions of different systems. In this study, a "turn-on" fluorescent probe for H2 S was developed. The probe, whose design is based on a familiar excited state intramolecular proton transfer (ESIPT) fluorophore bearing aggregation-induced emission (AIE) characteristics, was found to exhibit an 80-fold fluorescence enhancement along with a large Stokes shift upon the addition of H2 S. Furthermore, the probe was successfully utilized to detect H2 S in HeLa cells with both one-photon and two-photon microscopy.