Asymptomatic Hyperuricemia. (25th March 2016)

• Record Type: Journal Article
• Authors: Hosoya, Tatsuo; Nishio, Shinichiro
• Is Part Of: Journal of general and family medicine. Volume 17:Number 1(2016)
• Page Start: 71
• Page End: 76
• Publication Date: 2016-03-25
• Subjects: hyperuricemia -- gout -- chronic kidney disease -- cardiovascular disease; Primary care (Medicine) -- Periodicals; Family medicine -- Periodicals; Family Practice; Primary Health Care; Japan; Periodicals; 610
• DOI: 10.14442/jgfm.17.1_71
• Languages: English
• ISSNs: 2189-7948

Abstract

Abstract : According to recent study, hyperuricemia is not only a basic pathology of gout, but has been found that it is intimately related to the development and progress of hypertension, chronic renal disease (CKD), cardiovascular disease, and stroke. This means that hypertension, CKD and cardiovascular disease are caused by the direct effect (pro‐oxidant effect) of urate without going through urate crystal deposition. If the above issues can be indicated as clear evidence by treatment of interventional clinical trials, it can be thought that the treatment strategy for hyperuricemia to prevent organ damage will see substantial progress.