Elevated serum YKL-40 levels in patients with Kawasaki disease. (19th May 2017)

• Record Type: Journal Article
• Authors: Kim, K. Y.; Ahn, Y.; Kim, D. Y.; Kim, Ho-Seong; Kim, D. S.
• Is Part Of: Biomarkers. Volume 22:Number 3/4(2017)
• Page Start: 326
• Page End: 330
• Publication Date: 2017-05-19
• Subjects: Kawasaki disease -- acute phase reactant -- YKL-40; Biochemical markers -- Periodicals; 610.28
• DOI: 10.1080/1354750X.2016.1265000
• Languages: English
• ISSNs: 1354-750X

Abstract

Abstract: Context: YKL-40 is an inflammatory biomarker for endothelial dysfunction that may have a role in Kawasaki disease (KD). Objectives: We investigated the association of serum YKL-40 levels with KD and established laboratory parameters for YKL-40 levels and other inflammatory markers. Methods: YKL-40 levels and other inflammatory markers of 23 KD patients, 9 disease control patients and 11 age-matched healthy controls. Results: YKL-40 concentration in the serum of KD patients significantly increased during the acute disease phase compared with those of disease controls and healthy controls. Conclusions: Increased YKL-40 levels may provide a useful inflammatory marker for patients with KD.