Mixed-up about how to diagnose and treat mixed features in major depressive episodes. (8th March 2017)

• Record Type: Journal Article
• Authors: Stahl, Stephen M.
• Editors: McIntyre, Roger
• Is Part Of: CNS spectrums. Volume 22:Number 2(2017:Apr.)
• Page Start: 111
• Page End: 115
• Publication Date: 2017-03-08
• Subjects: Neuropsychiatry -- Periodicals; Nervous system -- Diseases -- Periodicals; Neurology -- Periodicals; 616.8005
• DOI: 10.1017/S1092852917000207
• Languages: English
• ISSNs: 1092-8529

Abstract

Abstract : The classical point of view—that major depressive episodes (MDEs), no matter what additional symptoms are present, should be treated first line with antidepressants—is now giving way to new a notion. The idea is that MDEs mixed with a few symptoms of mania/hypomania should be viewed very differently in terms of their natural history, clinical outcome, and treatment, and perhaps certain antipsychotics should be given as first-line treatment rather than antidepressant monotherapy.