Lack of Benefit With Combination Therapy for Clostridium difficile Infection. (6th February 2017)

• Record Type: Journal Article
• Authors: Njoku, Jessica C.; Van Schooneveld, Trevor C.; Rupp, Mark E.; Olsen, Keith M.; Qiu, Fang; Meza, Jane L.; Hermsen, Elizabeth D.
• Is Part Of: Infection control and hospital epidemiology. Volume 38:Number 5(2017)
• Page Start: 602
• Page End: 605
• Publication Date: 2017-02-06
• Subjects: Nosocomial infections -- Epidemiology -- Periodicals; Health facilities -- Sanitation -- Periodicals; Hospital buildings -- Sanitation -- Periodicals; Cross Infection -- Periodicals; Epidemiology -- Periodicals; Hospitals -- Periodicals; Infection Control -- Periodicals; 614.44
• DOI: 10.1017/ice.2016.320
• Languages: English
• ISSNs: 0899-823X

Abstract

Abstract : Limited data exist regarding combination therapy for Clostridium difficile infection (CDI). After adjusting for confounders in a cohort of patients with CDI and≥1 year old, combination therapy was not associated with significant differences in clinical outcomes, but it was associated with prolonged duration of therapy (1.22 days; 95% confidence interval, 1.03–1.44 days; P =.02). Infect Control Hosp Epidemiol 2017;38:602–605