Epigenetic and transcriptional effects operate on the SUPT3H and RUNX2 genes residing at the chromosome 6p21.1 osteoarthritis susceptibility locus and correlate with the association signal. (April 2017) - Rice, S.J.; Aubourg, G.; Sorial, A.K.; Deehan, D.; Loughlin, J.; Reynard, L.N.