Antenatal gastrointestinal anomalies in neonates subsequently found to have alveolar capillary dysplasia. Issue 5 (13th March 2017)

• Record Type: Journal Article
• Authors: Goel, Dimple; Oei, Ju Lee; Lui, Kei; Ward, Meredith; Shand, Antonia W.; Mowat, David; Gifford, Andrew J.; Loo, Christine
• Is Part Of: Clinical case reports. Volume 5:Issue 5(2017)
• Page Start: 559
• Page End: 566
• Publication Date: 2017-03-13
• Subjects: Alveolar capillary dysplasia -- FOXF1 gene -- gastrointestinal malformation -- misaligned pulmonary vein -- pulmonary hypertension; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.888
• Languages: English
• ISSNs: 2050-0904

Abstract

Key Clinical Message: Alveolar capillary dysplasia (ACD) is a rare condition with variable presentation and clinical course. Clinicians should consider this diagnosis in neonates presenting with nonlethal congenital gastrointestinal malformation, a period of well‐being after birth then unremitting hypoxemia and refractory pulmonary hypertension. Lung biopsy and FOXF1 gene testing may help in diagnosis. Abstract : Alveolar capillary dysplasia (ACD) is a rare condition with variable presentation and clinical course. Clinicians should consider this diagnosis in neonates presenting with nonlethal congenital gastrointestinal malformation, a period of well‐being after birth then unremitting hypoxemia and refractory pulmonary hypertension. Lung biopsy and FOXF1 gene testing may help in diagnosis.