Post-donation telephonic interview of blood donors providing an insight into delayed adverse reactions: First attempt in India. Issue 2 (April 2017)

• Record Type: Journal Article
• Authors: Tiwari, Aseem K.; Aggarwal, Geet; Dara, Ravi C.; Arora, Dinesh; Srivastava, Khushboo; Raina, Vimarsh
• Is Part Of: Transfusion and apheresis science. Volume 56:Issue 2(2017)
• Page Start: 141
• Page End: 146
• Publication Date: 2017-04
• Subjects: Adverse reaction -- Delayed adverse reaction (DAR) -- Immediate adverse reaction (IAR) -- Telephonic interview; Blood -- Transfusion -- Periodicals; Hemapheresis -- Periodicals; 615.39
• DOI: 10.1016/j.transci.2016.10.009
• Languages: English
• ISSNs: 1473-0502

Abstract

Abstract: Background: Blood donor experiences both immediate adverse reactions (IAR) and delayed adverse reactions (DAR). With limited published data available on the incidence of DAR, a study was conducted to estimate incidence and profile of DAR through telephonic interview. Materials and methods: Study was conducted over a 45-day period for consecutive volunteer whole blood donations at tertiary care hospital. Donors were divided into first-time, repeat and regular and were monitored for IAR. They were given written copy of post-donation advice. Donors were contacted telephonically three weeks post-donation and enquired about general wellbeing and specific DAR in accordance with a standard n international (International Society of Blood Transfusion) standard format. Results: Donors participated in the study of which 1.6% donors experienced an IAR. Much larger number reported DAR (10.3% vs.1.6% p < 0.0001). Further, DAR was presented as a variegated profile with bruise, painful arms and fatigue being the commonest. DARs were more common in females than males (25% vs. 10.3%, p < 0.02). Localized DAR like bruise and painful arms were more common in younger donors (age <50 years) whereas systemic DAR like fatigue was common in older donors (>50 years). First time (12.3%) and repeat donors (13.5%) had similar frequency of DAR but were lower among regular donors (6.7%). Conclusion: DARs are more common than IAR and are of different profile. Post-donation interview has provided an insight into donor experiences and can be used as a valuable tool in donor hemovigilance.