In situ generated cationic Pd(II)/bipyridine-catalyzed addition of arylboronic acids to N-sulfonyl-arylaldimines. Issue 21 (24th May 2017)

• Record Type: Journal Article
• Authors: Yang, Zhenyu; Ni, Yuxin; Liu, Rui; Song, Kaixuan; Lin, Shaohui; Pan, Qinmin
• Is Part Of: Tetrahedron letters. Volume 58:Issue 21(2017)
• Page Start: 2034
• Page End: 2037
• Publication Date: 2017-05-24
• Subjects: Cationic palladium(II) -- Bipyridine -- Arylboronic acid -- N-Sulfonyl arylaldimine -- Nucleophilic addition; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2017.04.035
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: Highly reactive cationic Pd(II)-bpy was in situ generated in CH3 NO2 . High yielded Pd(II)-catalytic addition to arylaldimines was optimized. Air and moisture insensitive Pd(II)-catalysis was developed. 12 of 13 examples yielded >90% and showed high functional groups tolerance. Abstract: An in situ generated cationic Pd(II)/bipyridine-catalyzed nucleophilic addition of arylboronic acids to N -sulfonyl arylaldimines was developed and optimized, and the reaction was proceeded highly efficiently and conveniently in CH3 NO2 . A series of arylboronic acids and N -sulfonyl arylaldimines were surveyed, and 12 of 13 examples gave 90∼96% yields.