Evolution of body weight parameters up to 3 years after solid organ transplantation: The prospective Swiss Transplant Cohort Study. Issue 3 (24th January 2017)

• Record Type: Journal Article
• Authors: Beckmann, Sonja; Nikolic, Nataša; Denhaerynck, Kris; Binet, Isabelle; Koller, Michael; Boely, Elsa; De Geest, Sabina
• Other Names: Berben Lut investigator.; Burkhalter Hanna investigator.; Claes Veerle investigator.; Helmy Remon investigator.; Kirsch Monika investigator.; Leppla Lynn investigator.; Mauthner Oliver investigator.; Struker Marian investigator.; Boehler Annette investigator.; Gerull Sabine investigator.; Huynh‐Do Uyen investigator.; Catana Emmanuelle investigator.; Simcox Amira investigator.; Seiler Annina investigator.; Klaghofer Richard investigator.; Künzler‐Heule Patrizia investigator.; Achermann Rita investigator.; Amico Patrizia investigator.; Aubert John‐David investigator.; Banz Vanessa investigator.; Beldi Guido investigator.; Benden Christian investigator.; Berger Christoph investigator.; Bochud Pierre‐Yves investigator.; Bucher Heiner investigator.; Bühler Leo investigator.; Carell Thierry investigator.; Chalandon Yves investigator.; de Rougemont Olivier investigator.; Dickenmann Michael investigator.; Duchosal Michel investigator.; Elkrief Laure investigator.; Fehr Thomas investigator.; Ferrari‐Lacraz Sylvie investigator.; Garzoni Christian investigator.; Soccal Paola Gasche investigator.; Gaudet Christophe investigator.; Giostra Emiliano investigator.; Golshayan Déla investigator.; Hadaya Karine investigator.; Halter Jörg investigator.; Heim Dominik investigator.; Hess Christoph investigator.; Hillinger Sven investigator.; Hirsch Hans H. investigator.; Hofbauer Günther investigator.; Immer Franz investigator.; Laesser Bettina investigator.; Lehmann Roger investigator.; Lovis Christian investigator.; Manuel Oriol investigator.; Marti Hans‐Peter investigator.; Martin Pierre Yves investigator.; Meylan Pascal investigator.; Mohacsi Paul investigator.; Morel Philippe investigator.; Mueller Ulrike investigator.; Mueller Nicolas J investigator.; Mueller‐McKenna Helen investigator.; Müller Antonia investigator.; Müller Thomas investigator.; Müllhaupt Beat investigator.; Nadal David investigator.; Pascual Manuel investigator.; Passweg Jakob investigator.; Rick Juliane investigator.; Roosnek Eddy investigator.; Rosselet Anne investigator.; Rothlin Silvia investigator.; Ruschitzka Frank investigator.; Schanz Urs investigator.; Schaub Stefan investigator.; Schnyder Aurelia investigator.; Seiler Christian investigator.; Stampf Susanne investigator.; Steiger Jürg investigator.; Stirnimann Guido investigator.; Toso Christian investigator.; Van Delden Christian investigator.; Venetz Jean‐Pierre investigator.; Villard Jean investigator.; Wick Madeleine investigator.; Wilhelm Markus investigator.; Yerly Patrick investigator.;
• Is Part Of: Clinical transplantation. Volume 31:Issue 3(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-01-24
• Subjects: body mass index -- obesity -- organ transplantation -- prospective study -- underweight -- weight gain; Transplantation of organs, tissues, etc -- Periodicals; 617.95
• DOI: 10.1111/ctr.12896
• Languages: English
• ISSNs: 0902-0063

Abstract

Abstract: Obesity and weight gain are serious concerns after solid organ transplantation (Tx); however, no unbiased comparison regarding body weight parameter evolution across organ groups has yet been performed. Using data from the prospective nationwide Swiss Transplant Cohort Study, we compared the evolution of weight parameters up to 3 years post‐Tx in 1359 adult kidney (58.3%), liver (21.7%), lung (11.6%), and heart (8.4%) recipients transplanted between May 2008 and May 2012. Changes in mean weight and body mass index (BMI) category were compared to reference values from 6 months post‐Tx. At 3 years post‐Tx, compared to other organ groups, liver Tx recipients showed the greatest weight gain (mean 4.8±10.4 kg), 57.4% gained >5% body weight, and they had the highest incidence of obesity (38.1%). After 3 years, based on their BMI categories at 6 months, normal weight and obese liver Tx patients, as well as underweight kidney, lung and heart Tx patients had the highest weight gains. Judged against international Tx patient data, the majority of our Swiss Tx recipients' experienced lower post‐Tx weight gain. However, our findings show weight gain pattern differences, both within and across organ Tx groups that call for preventive measures.