Hypoxic–ischaemic brain injury following cardiac arrest. Issue 5 (May 2017)

• Record Type: Journal Article
• Authors: Howard, Robin S.
• Is Part Of: Anaesthesia and intensive care medicine. Volume 18:Issue 5(2017:May)
• Page Start: 244
• Page End: 248
• Publication Date: 2017-05
• Subjects: Coma -- hypoxic–ischaemic brain injury -- induced hypothermia; Anesthesiology -- Periodicals; Critical care medicine -- Periodicals; Anesthesia -- Periodicals; Intensive care -- Periodicals; Electronic journals; Periodicals; 617.9605
• DOI: 10.1016/j.mpaic.2017.02.005
• Languages: English
• ISSNs: 1472-0299

Abstract

Abstract: Hypoxic–ischaemic brain injury (HIBI) has become an increasingly common cause of admission to intensive care units (ICUs) and prolonged or permanent neurological disability. It is essential to provide an accurate prognosis to guide management. Following restoration of spontaneous circulation (ROSC) clinical assessment is often difficult and ancillary investigation is necessary. Outcome depends on the severity of the initial insult, the effectiveness of immediate resuscitation and transfer, and the post-resuscitation management on the ICU. Some patients remain profoundly impaired and others may develop complications including myoclonic epilepsy, cognitive impairment, border-zone infarction and movement disorders. The management of patients with HIBI presents considerable clinical, ethical and legal difficulties.