Generation, spectroscopic characterization and antioxidant activity of tetracoordinate and hexacoordinate complexes of diethylgermanium(IV) of relatively sterically undemanding N-protected amino acids and sterically demanding heterocyclic β-diketones containing radical sensitive Ge-O bond. (4th May 2017)

• Record Type: Journal Article
• Authors: Maheshwari, Karuna; Srivastava, Manish Kumar; Saxena, Sanjiv; Jain, Asha
• Is Part Of: Phosphorus, sulfur, and silicon and the related elements. Volume 192:Number 5(2017)
• Page Start: 506
• Page End: 512
• Publication Date: 2017-05-04
• Subjects: Diethylgermanium(IV) complexes -- N-protected amino acids -- heterocyclic β-diketones -- antioxidant activity; Sulfur compounds -- Periodicals; Organosulfur compounds -- Periodicals; Phosphorus compounds -- Periodicals; Organophosphorus compounds -- Periodicals; Silicon compounds -- Periodicals; Organosilicon compounds -- Periodicals; 546
• DOI: 10.1080/10426507.2016.1266356
• Languages: English
• ISSNs: 1042-6507

Abstract

ABSTRACT: Two new sets of diethylgermanium(IV) complexes of the types Et2 GeA2 and Et2 GeB2 have been generated by the reactions of diethylgermanium(IV) dichloride with sodium salts of N-protected amino acids (AH) [where AH =, R = -CH(CH3 )C2 H5 : A1 H, R = -CH2 CH(CH3 )2 : A2 H, R = -CH(CH3 )2 : A3 H] and with sodium salts of sterically demanding heterocyclic β-diketones (BH) [where BH =, R' = -C6 H5 : B1 H, R' = -p-(Cl)C6 H4 : B2 H, R' = -CH3 : B3 H, R = -C2 H5 : B4 H], respectively in 1:2 molar ratios in refluxing dry benzene. Plausible structures of these complexes were suggested on the basis of physico-chemical and spectroscopic studies. It is suggested that the complexes of the types Et2 GeA2 and Et2 GeB2 contain four coordinated and six coordinated germanium centers, respectively. The ligands and organogermanium(IV) complexes were evaluated for their free radical scavenging activity by DPPH method. These compounds/complexes demonstrate potential antioxidant activity. GRAPHICAL ABSTRACT: