Perinatal outcomes and cost-effectivity of the assisted reproduction pregnancies with advanced age: A retrospective analysis. (19th May 2017)

• Record Type: Journal Article
• Authors: Yilmaz, Nafiye; Kara, Mustafa; Coskun, Bugra; Kaba, Metin; Erkilinc, Selçuk; Yenicesu, Okan; Erkaya, Salim
• Is Part Of: Journal of obstetrics and gynaecology. Volume 37:Number 4(2017)
• Page Start: 450
• Page End: 453
• Publication Date: 2017-05-19
• Subjects: Advanced age -- infertility -- IVF-ICSI -- perinatal outcomes -- cost-effectivity; Obstetrics -- Periodicals; Gynecology -- Periodicals; 618.05
• DOI: 10.1080/01443615.2016.1251887
• Languages: English
• ISSNs: 0144-3615

Abstract

Abstract: We demonstrated the IVF-ICSI results, perinatal outcomes and cost-effectivity of the patients with advanced age at a tertiary centre. A total of 456 patients categorised into two groups according to age: group 1 ( n = 158) (≥39years) and group 2 ( n = 298) (<39years) were analysed retrospectively. In addition, subgroup analysis was performed according to the 40 years cut-off. Clinical pregnancy rate was significantly different between the groups ( p < .001). Preterm delivery (< 37 gestational week) and low birth weight (< 2500 g) were significantly higher in advanced aged women than youngsters ( p < .001). Mean expense per cycle for hormonal stimulation of IVF-ICSI was 1058.9 and 723.5 USD in groups 1 and 2, respectively ( p < .001). Mean expense per pregnancy was 9294.7 and 1874.8 USD in groups 1 and 2, respectively ( p < .001). Our study showed that perinatal outcomes and cost-effectivity might be adversely affected with increasing age.