Interferon-I: The Pièce de Résistance of HIV-1 Transmission?. Issue 5 (May 2017)

• Record Type: Journal Article
• Authors: Tully, Damien C.; Claiborne, Daniel T.; Allen, Todd M.
• Is Part Of: Trends in microbiology. Volume 25:Issue 5(2017)
• Page Start: 332
• Page End: 334
• Publication Date: 2017-05
• Subjects: HIV -- Transmission -- Bottleneck -- Interferon -- Resistance -- Mucosal; Microbiology -- Periodicals; Infection -- Periodicals; Virulence (Microbiology) -- Periodicals; Infection -- Periodicals; Microbiology -- Periodicals; Virulence -- Periodicals; Microbiologie -- Périodiques; Infection -- Périodiques; Virulence (Microbiologie) -- Périodiques; Infection; Microbiology; Virulence (Microbiology); 579
• DOI: 10.1016/j.tim.2017.02.010
• Languages: English
• ISSNs: 0966-842X

Abstract

Abstract : Despite the extensive viral quasispecies that develops in an individual during the course of HIV-1 infection, transmission is typically established by a single donor viral variant. Recent studies now provide insight into the phenotypic properties influencing this selection process at transmission, including the contribution of resistance to type I interferons.