The potential of unsaturated polyesters in biomedicine and tissue engineering: Synthesis, structure-properties relationships and additive manufacturing. (May 2017)

• Record Type: Journal Article
• Authors: Gonçalves, F.A.M.M.; Fonseca, A.C.; Domingos, M.; Gloria, A.; Serra, A.C.; Coelho, J.F.J.
• Is Part Of: Progress in polymer science. Volume 68(2017)
• Page Start: 1
• Page End: 34
• Publication Date: 2017-05
• Subjects: AA adipic acid -- AcA acrylic acid -- AIBN α, α′-azoisobutyronitrile -- AM additive manufacturing -- BM 4, 4-bismaleimidodiphenylmethane -- BMP butyl-3-mercapto propionate -- BPO benzoyl peroxide -- BOD biochemical oxygen demand -- CA Candida Antarctica -- CAD computer-aided design -- CALB Lipase B from Candida Antarctica -- CAM computer aided manufacturing -- CDM 1, 4-cyclohexanedimethanol -- CDRSP Centre for Rapid and Sustainable Product Development (Portugal) -- CHD cyclohexanediol -- CHMD 1, 4-cyclohexanedimethanol -- ε-CL ε-caprolactone -- CTNB carboxy terminated nitrile rubber -- CQ camphorquinone -- DACC 3, 4-diacetoxycinnamoyl chloride -- DAHs dianhydrohexitols -- DCC dicyclohexylcarbodiimide -- DEF diethyl fumarate -- DEG diethylene glycol -- DHCA 3, 4-dihydroxycinnamic acid -- DHO 6, 7-dihydro-2(5H)-oxepinone -- DMAMEA dimethylamino methyl ethylacrylate -- DMAP dimethylaminopyridine -- DMD 2, 2-dimethyl-1, 3-propanediol -- DMI dimethyl itaconate -- DMTA dynamic mechanical thermal analysis -- DN double network -- DSC differential scanning calorimetry -- EG ethylene glycol -- EO ethylene oxide -- EVA ethylene vinyl acetate -- FA fumaric acid -- FAME fatty acid methyl ester -- FU diethyl fumarate -- FUPR fluorinated modified unsaturated polyester resin -- GL diethyl trans-glutaconate -- Gl globalide -- HDA 10-hydroxycaproic acid -- HDT heat deflection temperature -- HEMA 2-hydroxyethyl methacrylate -- HMA trans-β-hydromuconic acid -- HM diethyl trans-β-hydromuconate -- HPR hydroxyl-ended hyperbranched polyester resin -- HTNR hydroxyl terminated natural rubber -- HTPB hydroxyl terminated polybutadiene -- IA itaconic acid -- IM isomannide -- IS isosorbide -- IT diethyl itaconate -- MA maleic anhydride -- mCPBA m-chloroperbenzoic acid -- MEKP methyl ethyl ketone peroxide -- MH 6-mercapto-1-hexanol -- MM Mucor miehei -- MMA methyl methacrylate -- MPD 2-methyl-1, 3-propanediol -- MPDO 2-methyl-1, 5-pentanediol -- nACA N-acetylcysteamine -- NPG neopentylglycol -- NVP N-vinylpyrrolidone -- OMIS oligo(isosorbide maleate) -- PBF poly(butylene fumarate) -- PBSI poly(butylene succinate-co-itaconate) -- PC Pseudomonas cepacia -- PCL poly(ε-caprolactone) -- PCLF poly(ε-caprolactone-co-fumarate) -- PCL-PFPE-PCL poly(ε-caprolactone)-perfluorpolyether- poly(ε-caprolactone) -- PD 1, 2-propanediol -- PEFS poly(ethylene fumarate-co-sebacate) -- PEG poly(ethylene glycol) -- PEGF poly(ethylene glycol-co-fumarate) -- PEGF-co-PHMCF poly(ethylene glycol fumarate-co-hexamethylene carbonate- fumarate) -- PET poly(ethylene terephthalate) -- P(FA-GLY-BA) poly(fumaric acid-glycol-brassylic acid) -- P(FA-GLY-DDDA) poly(fumaric acid-glycol-dodecanedioic acid) -- P(FA-GLY-PA) poly(fumaric acid-glycol-pentadecanedioic acid) -- P(FA-GLY-SA) poly(fumaric acid-glycol-sebacic acid) -- P(FA-GLY-TA) poly(fumaric acid-glycol-tetradecanedioic acid) -- PG propylene glycol -- PGA poly(glycolic acid) -- PGl polyglobalide -- PhA phthalic anhydride -- PHEMA poly(2-hydroxyethyl methacrylate) -- PHFS poly(hydroquinone fumarate-co-sebacate) -- PHMCA poly(hexamethylene carbonate) diacrylate -- PHV poly(hydroxy valerate) -- PHMCF poly(hexamethylene carbonate-fumarate) -- PRFS poly(resorcinol fumarate-co-sebacate) -- PLA poly(lactic acid) -- PLLA poly(l-lactic acid) -- P(MA-GLY-SA) poly(maleic anhydride-glycol-sebacic acid) -- PMMA poly(methyl methacrylate) -- PO propylene oxide -- PPF poly(propylene fumarate) -- PPFS poly(propylene fumarate-co-sebacate) -- PPS poly(1, 2-propylene succinate) -- PSAGE poly(3-allyloxy-1, 2-propylene succinate) -- PTSA p-toluenesulfonic acid monohydrate -- PU polyurethane -- ROP ring opening polymerization -- SA succinic acid -- SebA sebacic acid -- SEM scanning electron microscopy -- SLA stereolithography -- SN single network -- Sorb Sorbitol -- SPD (S)-(+)-1, 2-propanediol -- STLA stereo-thermal-lithography -- TC tamoxifen citrate -- TE tissue engineering -- TEG triethylene glycol -- TGA thermogravimetric analysis -- THPA cyclohex-4-ene-dicarboxylic anhydride -- TMP trimethylolpropane -- TPA terephthalic acid -- TPP two-photon polymerization -- UM unsaturated monomer -- UPs unsaturated polyesters -- UPHR unsaturated hyperbranched polyester resin -- UPRs unsaturated polyester resins; Unsaturated polyesters -- Structure/properties relationships -- Tissue engineering -- Additive manufacturing -- Stereolithography processes; Polymers -- Periodicals; Polymerization -- Periodicals; Polymers -- Industrial applications -- Periodicals; Polymères -- Périodiques; Polymérisation -- Périodiques; 547.7
• DOI: 10.1016/j.progpolymsci.2016.12.008
• Languages: English
• ISSNs: 0079-6700

Abstract

Abstract: The success of Tissue Engineering (TE) based approaches is strongly dependent on the development of novel biomaterials for the design of 3D matrices with tailored biomechanical properties to promote the regeneration of human tissues and organs. This review covers the critical aspects related with the preparation of new unsaturated polyester (UP) resin formulations with suitable biological, chemical, thermal and morphological properties for the additive manufacturing (AM) of TE constructs. In this context, the basic principles of available AM technologies, with a special focus on novel stereolithography processes such as microstereolithography (micro-SLA), stereo-thermal-lithography (STLA), two-photon polymerization (TPP) and nanostereolithography (nano-SLA), are also presented and discussed. Ultimately, the present review will provide a better insight into the limitations and potential of combining UP and AM towards the rationale design/fabrication of complex artificial tissue substitutes.