Tailor-made hydrophobic deep eutectic solvents for cleaner extraction of polyprenyl acetates from Ginkgo biloba leaves. (20th May 2017)

• Record Type: Journal Article
• Authors: Cao, Jun; Yang, Meng; Cao, Fuliang; Wang, Jiahong; Su, Erzheng
• Is Part Of: Journal of cleaner production. Volume 152(2017)
• Page Start: 399
• Page End: 405
• Publication Date: 2017-05-20
• Subjects: Polyprenyl acetates -- Ginkgo biloba leaves -- Extraction -- Hydrophobic deep eutectic solvents -- Designer solvent; Factory and trade waste -- Management -- Periodicals; Manufactures -- Environmental aspects -- Periodicals; Déchets industriels -- Gestion -- Périodiques; Usines -- Aspect de l'environnement -- Périodiques; 628.5
• DOI: 10.1016/j.jclepro.2017.03.140
• Languages: English
• ISSNs: 0959-6526

Abstract

Abstract: Deep eutectic solvents (DESs), especially hydrophilic DESs, have been considered green substitutes to conventional organic solvents for bioactive compounds extraction. This study provided a practical example demonstrating the efficiency of hydrophobic DESs as designer solvent to extract polyprenyl acetates from Ginkgo biloba leaves. A hydrophobic ternary DES named as MCO gave the highest extraction yield for polyprenyl acetates during the initial screening. It was tailor-made from methyl trioctyl ammonium chloride, capryl alcohol and octylic acid at a molar ratio of 1:2:3 by systematically optimizing the DES component type, molar ratio and number. With MCO-based extraction, the operational factors influencing the extraction yield were further optimized by statistical method. The model for the extraction of polyprenyl acetates was well established and verified. Extraction yield of 84.11 ± 0.7366 was obtained at the optimal conditions, which was much higher than those of conventional hydrophobic organic solvents (petroleum ether and n -hexane). Moreover, excellent recovery of polyprenyl acetates from MCO extraction solution was obtained by macroporous resin AB-8 or DM130 adsorption. This study demonstrated that not only hydrophilic DESs but also hydrophobic DESs can be adopted as solvents for bioactive compounds extraction from biomass. Highlights: Dozens of hydrophobic deep eutectic solvents (DESs) were prepared in this work. Hydrophobic DESs were used to extract bioactive compounds from plant biomass. This work showcases the tunability of hydrophobic DESs as designer solvents. A tailor-made ternary DES showed higher extraction yield than conventional organic solvents. DESs can be tuned with different hydrophilicity or hydrophobicity for extraction.