Synthesis of Tetrasubstituted Furans by Using Photoredox‐Catalyzed Coupling of 2‐Bromo‐1, 3‐dicarbonyl Compounds with Silyl Enol Ethers. Issue 4 (23rd November 2016)

• Record Type: Journal Article
• Authors: Han, Yue‐Yue; Jiao, Yan‐Yan; Ren, Daan; Hu, Zhentao; Shen, Sheng; Yu, Shouyun
• Is Part Of: Asian journal of organic chemistry. Volume 6:Issue 4(2017)
• Page Start: 414
• Page End: 417
• Publication Date: 2016-11-23
• Subjects: iridium -- oxygen heterocycles -- photochemistry -- radicals -- silyl enol ethers; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; 547.005
• DOI: 10.1002/ajoc.201600489
• Languages: English
• ISSNs: 2193-5807

Abstract

Abstract: A practical and efficient method has been developed for the preparation of polysubstituted furans by using a visible‐light‐promoted photoredox approach. The one‐pot synthesis involves a radical cyclization/deprotection/aromatization reaction sequence that proceeds smoothly under mild conditions, which makes this transformation a powerful tool for the synthesis of a variety of highly substituted furans. Abstract : Light Ir up : An efficient method for the synthesis of tetrasubstituted furans by using a photoredox‐catalyzed coupling of 2‐bromo‐1, 3‐dicarbonyl compounds with silyl enol ethers has been developed.