Regioselective TfOH-mediated hydroamidation of ynamides with nitriles. Issue 19 (11th May 2017)
- Record Type:
- Journal Article
- Title:
- Regioselective TfOH-mediated hydroamidation of ynamides with nitriles. Issue 19 (11th May 2017)
- Main Title:
- Regioselective TfOH-mediated hydroamidation of ynamides with nitriles
- Authors:
- Wang, Wan-Shu
Chen, Ping
Tang, Yu - Abstract:
- Abstract: A new TfOH-mediated reaction of ynamides with nitriles as nucleophiles has been developed. The reaction works efficiently under mild reaction conditions to afford a new class of α-acylaminoenamides readily via the intermediacy of keteniminium ion. The reaction displays generality and a broad substrates scope. Additionally, the α-acylaminoenamides could be transformed to highly substituted pyridine, 4-aminopyrimidine or isoquinoline cores. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 73:Issue 19(2017)
- Journal:
- Tetrahedron
- Issue:
- Volume 73:Issue 19(2017)
- Issue Display:
- Volume 73, Issue 19 (2017)
- Year:
- 2017
- Volume:
- 73
- Issue:
- 19
- Issue Sort Value:
- 2017-0073-0019-0000
- Page Start:
- 2731
- Page End:
- 2739
- Publication Date:
- 2017-05-11
- Subjects:
- Ynamides -- Trifluoromethanesulfonic acid -- Nitriles -- Acylaminoenamides -- Keteniminium ions
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2017.03.060 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 1114.xml