A facile approach for the trifluoromethylthiolation of methylenecyclopropanes. Issue 1 (27th October 2016)

• Record Type: Journal Article
• Authors: Chen, Min-Tao; Tang, Xiang-Ying; Shi, Min
• Is Part Of: Organic chemistry frontiers. Volume 4:Issue 1(2017)
• Page Start: 86
• Page End: 90
• Publication Date: 2016-10-27
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c6qo00536e
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : Trifluoromethylthiolation of methylenecyclopropanes (MCPs) has been developed by using AgSCF3 /Na2 S2 O8 as a trifluoromethylthiolation source (SCF3 ) to give trifluoromethylthiolated 1, 2-dihydronaphthalene derivatives in moderate to good yields. Abstract : A facile approach for the trifluoromethylthiolation of methylenecyclopropanes (MCPs) has been developed by using AgSCF3 /Na2 S2 O8 as a trifluoromethylthiolation source (SCF3 ) to give trifluoromethylthiolated 1, 2-dihydro-naphthalene derivatives in moderate to good yields, and the reaction has been proven to go through a radical-type pathway. The products can easily be aromatized upon oxidation, offering a new method for the construction of trifluoromethylthiolated naphthalenes.